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・ Pan-African colours
・ Pan-African Congress
・ Pan-African Congress of Mathematicians
・ Pan-African Democratic Party
・ Pan-African e-Network project
・ Pan-African Federation
・ Pan de Guajaibón
・ Pan de jamón
・ Pan de muerto
・ Pan de Pascua
・ Pan de queso
・ Pan de yuca
・ Pan Deng
・ Pan Desuyo!
・ Pan Dingxin
PAN domain
・ Pan dulce
・ Pan En
・ Pan European Game Information
・ Pan European ICT & eBusiness Network for SME
・ Pan Européenne Air Service
・ Pan evaporation
・ Pan Fengzhen
・ Pan flute
・ Pan frying
・ Pan Fu
・ Pan Fusheng
・ Pan Gate
・ Pan Geng
・ Pan Glacier


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PAN domain : ウィキペディア英語版
PAN domain

PAN domains have significant functional versatility fulfilling diverse biological roles by mediating protein-protein and protein-carbohydrate interactions. These domains contain a hair-pin loop like structure, similar to that found in knottins but with a different pattern of disulfide bonds.
It has been shown that the N-terminal domains of members of the plasminogen/hepatocyte growth factor family, the apple domains of the plasma prekallikrein/coagulation factor XI family, and domains of various nematode proteins belong to the same module superfamily, the PAN module.〔 The PAN domain contains a conserved core of three disulfide bridges. In some members of the family there is an additional fourth disulfide bridge that links the N- and C-termini of the domain.
In native plasminogen the PAN domain is associated with five Kringle domains. The interactions between the PAN domain and the kringles play a critical role in stabilising the quaternary complex of the native plasminogen;
==References==


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